Making up and breaking up: the tortuous ways of the vascular wall.
نویسندگان
چکیده
The concept that blood pressure influences vessel wall composition and structure is well established. Any alterations in stretch (caused by changes in blood pressure) solicit counteracting radial and tangential forces, driving transformations in the vessel wall that aim to accommodate the new conditions and to ultimately restore basal levels of tensile stress.1–3 Thus, when tensile stress increases because of a rise in arterial pressure, smooth muscle cell hypertrophy and collagen and elastin contents augment. Inversely, when the circumferential stress falls, the wall undergoes atrophy.4,5
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ورودعنوان ژورنال:
- Arteriosclerosis, thrombosis, and vascular biology
دوره 25 5 شماره
صفحات -
تاریخ انتشار 2005